Ferocity that entangle cells mesothelial at human body, entered pleura, peritoneum, perikardium, and testis, known as ferocious mesothelioma, either that local or difus.
Most, but not all, case ferocious mesothelioma (malignant mesothelioma) at pleural (lung cancer) usually relate to presentation from asbestos.
Patient with ferocious mesothelioma pleura, 77% has been hit asbestos was at its the past.
Diagnosis difficult mesothelioma uphold because the result of analysis of effusion fluid from cancer usually is not most diagnostic.
Mesothelioma more public happens at men than woman and that happened most often at the age of fifth decade till decade 7th.
A large part of cases (around 90%) from malignant mesothelioma happened in pleura.
From picture histologi is existed 3 types mesothelioma that is mesothelioma sarcomatous, epitel, and mixture (mixed).
Pleural mesothelioma usually started as the plaque and nodul that join to produce sheetlike neoplasm.
Tumor Growth usually started at down section chest, tumor can attack diaphragm and blanket lung surface and gap interlobaris.
When disease expand, often extend to parenkim paru, chest wall and wall mediastinum.
Pleural mesothelioma can disseminate to throat, flank, backbone, pleksus brakialis, and vena cava superior.
Asbestos, amphibole asbestos, asbestos-crocidolite, and amosite asbestos especially, is main carcinogen involveds in patogenesis.
Asbestos Presentation chrysotil is related to mesothelioma lower incident.
Industry Area that often related to the happening of mesotelioma consequence of asbestos presentation is entered mining industry, ship-building that entangle the usage of asbestos, cement asbestos making, ceramic, hulling paper, auto parts, and factory of train repair.
Clinic Manifestation or clinic symptom that happened at mesothelioma that is:
- Dyspnea and pain in bone nonpleuritic chest wall is most commonly symptom happens at ferocious mesothelioma. (Around 60-90% from patient experience of symptom of chest pain in bone or dyspnea.)
- At patient with ferocious mesothelioma, finding of effusion physical pleura usually known with percussion and auskultassion.
- At case that seldom, ferocious mesothelioma as cord compression, brachial plexopathy, Horner syndrome, or superior vena cava syndrome. Death usually caused by infection or respiration failure from growth mesothelioma.
- Main Area that often happened at pleura (87%), peritoneum (5,1%), and perichardium (0,4%).