The following clinical trials for mesothelioma currently looking for participants as of April 2009. The study, ordered by their relevance to malignant mesothelioma. To more information about these or others in the process of clinical trials, click here.
Cisplatin, Pemetrexed, and imatinib Mesylate in Malignant Mesothelioma
Condition: Mesothelioma
Interventions: Drug: Cisplatin; Drug: imatinib Mesylate; Drug: Pemetrexed
Video-Assisted Surgery or Talk Pleurodesis in Treating Patients With Malignant Mesothelioma
Condition: Malignant Mesothelioma; Metastatic Cancer
Interventions: Other: talc; Procedure: thoracoscopic surgery therapy; Procedure: therapeutic thoracoscopy; Procedure: therapeutic videothoracoscopy
Dasatinib in resectable malignant pleural Mesothelioma
Condition: Malignant Pleural Mesothelioma
Interventions: Drug: Dasatinib
Immunotoxin Therapy, Pemetrexed, and Cisplatin in Treating Patients With Malignant Pleural Mesothelioma That Can not Be Removed by Surgery
Condition: Malignant Mesothelioma
Interventions: Biological: SS1 (dsFv)-PE38 immunotoxin; Drug: cisplatin; Drug: pemetrexed disodium; Other: immunoenzyme technique; Other: immunohistochemistry staining method; Other: pharmacological study; Procedure: quality-of-life assessment
Extrapleural pneumonectomy / Pleurectomy Decortication, IHOC Cisplatin and gemcitabine With Amifostine and sodium thiosulfate Cytoprotection for resectable malignant pleural Mesothelioma
Condition: Malignant Pleural Mesothelioma
Interventions: Procedure: Extrapleural pneumonectomy (EPP), Pleurectomy / Decortication; Drug: cisplatin; Drug: gemcitabine; Drug: amifostine; Drug: sodium thiosulfate
Study CBP501 + Pemetrexed + Cisplatin in Patients With Solid Tumors (Phase I) and Patients With Malignant Pleural Mesothelioma (Stage II)
Condition: Malignant Pleural Mesothelioma; MPM; Solid Tumors
Interventions: Drug: pemetrexed, cisplatin and CBP501; Drug: pemetrexed and cisplatin
Early diagnosis and Lung Cancer Mesothelioma in Prior Asbestos Workers
Condition: Lung cancer; Mesothelioma
Interventions: observational study
Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma
Condition: Malignant Mesothelioma
Interventions: Drug: dasatinib; Other: immunoenzyme technique; Other: immunohistochemistry staining method; Other laboratory markers analysis
Tomotherapy Treatment for Mesothelioma
Condition: Mesothelioma
Interventions: Procedure: Tomotherapy
Bortezomib in Treating Patients With Malignant Pleural Mesothelioma
Condition: Malignant Mesothelioma
Interventions: Drug: bortezomib; Procedure: quality-of-life assessment
AZD2171 in Treating Patients With Malignant Mesothelioma That Can not Be Removed By Surgery
Conditions: Mesothelioma Malignant
Interventions: Drug: cediranib maleate; Other laboratory markers analysis
Bortezomib and Cisplatin as First-Line Therapy in Patients With Treatment Malignant Mesothelioma
Condition: Malignant Mesothelioma
Interventions: Drug: bortezomib; Drug: cisplatin
Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
Condition: Malignant Mesothelioma
Interventions: Drug: cisplatin; Drug: pemetrexed disodium; Other laboratory marker analysis; Procedure: adjuvant therapy; Procedure: conventional surgery; Procedure: neoadjuvant therapy; Procedure: quality-of-life assessment; radiation: radiation therapy
Antineoplaston Therapy in Treating Patients With Advanced Mesothelioma
Condition: Malignant Mesothelioma
Interventions: Drug: antineoplaston A10; Drugs: antineoplaston AS2-1
Dendritic cells-Based Immunotherapy in Mesothelioma
Condition: Malignant Pleural Mesothelioma
Interventions: Biological: tumor lysate-loaded autologous dendritic cells
Sunitinib in Treating Patients With Advanced Malignant Pleural Mesothelioma
Condition: Malignant Mesothelioma
Interventions: Drug: sunitinib malate
Combination Chemotherapy With or Without Surgery and Radiation Therapy in Treating Patients With Mesothelioma That Can Removed By Surgery
Condition: Malignant Mesothelioma
Interventions: drugs: chemotherapy; Procedure: adjuvant therapy; Procedure: conventional surgery; Procedure: neoadjuvant radiation therapy: radiation therapy
Pemetrexed, Cisplatin, and Vitamin B12 in Treating Patients With Mesothelioma of the Chest That Can not Be Removed by Surgery
Condition: Malignant Mesothelioma
Interventions: Dietary Supplements: Vitamin B12; Drug: cisplatin; Drug: pemetrexed disodium; genetics: analysis of gene expression; Other laboratory marker analysis; Other: pharmacological study
Everolimus in Treating Patients With Malignant Pleural Mesothelioma That Can not Be Removed By Surgery
Kondisi: Malignant Mesothelioma
Interventions: Drug: everolimus
Study of Patients With Non-Small Cell Lung Cancer, Esophageal Cancer, Malignant Pleural Mesothelioma, or Chest Wall Mediastinal neoplasms, or Lung Cancer Metastasis From Non-Thoracic Origin
Condition: Esophageal Cancer; Lung Cancer; Malignant Mesothelioma; Metastatic Cancer
Interventions: Genetic: DNA methylation analysis; genetic: analysis of gene expression; Procedure: bronchoscopy; Procedure: endoscopic biopsy; Procedure: needle biopsy
Cisplatin, and bevacizumab for Pemetrexed untreated malignant Mesothelioma
Condition: Mesothelioma
Interventions: Drug: bevacizumab; Drug: cisplatin; Drug: pemetrexed
An Efficacy Study Milataxel (TL139) Administered Orally for Malignant Mesothelioma
Condition: Mesothelioma
Interventions: Drug: Milataxel
Eloxatin ® Plus gemcitabine chemotherapy for Mesothelioma
Condition: Mesothelioma
Interventions: Drug: Oxaliplatin / gemcitabine
Efficacy and Safety Study With A Treat Vandetanib for inoperable malignant or relapse Mesothelioma
Condition: Mesothelioma
Interventions: Drug: vinorelbine; Drug: Vandetanib
Suberoylanilide Hydroxamic Acid (SAHA) Versus Placebo in Advanced Malignant Pleural Mesothelioma
Condition: Mesothelioma; Lung Cancer
Interventions: Drug: Comparison: Suberoylanilide Hydroxamic Acid (SAHA); Drugs: Comparison: Placebo
Study carboplatin and vinorelbine in malignant pleural Mesothelioma
Condition: Malignant Pleural Mesothelioma
Interventions: Drug: carboplatin and vinorelbine
Chemotherapy was followed by a study using Intensity Modulated Radiation Therapy to the pleura in Patients With Advanced Malignant Pleural But Local Unresectable Mesothelioma
Condition: Mesothelioma
Interventions: Other: Pemetrexed + Cisplatin and Intensity Modulated Radiation Therapy
Pharmacokinetics, Safety, and Efficacy Effects on Oral LBH589 in Patients With Advanced or Metastatic dextromethorphan Non-Small Cell Lung Cancer or Malignant Pleural Mesothelioma
Condition: Carcinoma, Non-Small-Cell Lung; Mesothelioma
Interventions: Drug: LBH 589
Sorafenib in Previously Treated Malignant Mesothelioma
Condition: Mesothelioma
Interventions: Drug: Sorafenib
An Efficacy Study of MORAb-009 in Subjects With Pleural Mesothelioma
Condition: Malignant Pleural Mesothelioma
Interventions: Drug: MORAb-009 by IV on days 1 and 8 every 21 days for 6 cycles.
Phase II Study of bevacizumab, Pemetrexed and carboplatin as First-Line Therapy in Malignant Pleural Mesothelioma
Condition: Mesothelioma
Interventions: Drug: bevacizumab, Pemetrexed, carboplatin
Lung-Sparing Treatment of pleural Trimodal Mesothelioma
Conditions: Pleural Mesothelioma
Interventions: Drug: Doxorubicin and cisplatin (intrapleural) + cisplatin and pemetrexed (systemic); Drug: Cisplatin and doxorubicin (intrapleural)
Decitabine and FR901228 in Treating Patients With Advanced Lung Cancer, Esophageal Cancer, Pleural Mesothelioma, or Lung Metastases
Condition: Esophageal Cancer; Lung Cancer; Malignant Mesothelioma; Metastatic Cancer
Interventions: Drug: celecoxib; Drug: decitabine; Drug: romidepsin
Mesothelioma Avastin Plus Pemetrexed-Cisplatin Study
Condition: Mesothelioma
Interventions: Drug: Standard Chemotherapy (Pemetrexed and Cisplatin); Drugs: Standard Chemotherapy (Pemetrexed and Cisplatin) + bevacizumab
Phase I Dose-Escalation Study of Azacitidine In Combination With Temozolomide
Condition: Soft Tissue Sarcoma; Mesothelioma
Interventions: Drug: Azacitidine In Combination With Temozolomide
Pleurectomy / Decortication With Intraoperative Intrathoracic / heated intraperitoneal Cisplatin With Sodium thiosulfate
Conditions: Pleural Mesothelioma; Malignant Pleural Mesothelioma
Interventions: Drug: Cisplatin; Drug: sodium thiosulfate; Drug: ALIMTA
Carboplatin, bevacizumab, and Pemetrexed in the First-Line Treatment of Patients With MPM
Condition: Mesothelioma
Interventions: Drug: carboplatin, bevacizumab, and Pemetrexed
Neoadjuvant short Hemithoracic IMRT for MPM
Condition: Malignant Pleural Mesothelioma
Interventions: Other: Pre-op RT + / - chemotherapy
Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors
Condition: Breast Cancer; colorectal cancer; Head and Neck Cancer; Lung Cancer; Malignant Mesothelioma; pancreatic cancer; Prostate Cancer; Sarcoma
Interventions: Drug: cisplatin; Drug: pemetrexed disodium; Drug: sorafenib tosylate
FR901228 and Flavopiridol in Treating Patients With Advanced Lung, Esophageal, or Pleural Cancer
Condition: Esophageal Cancer; Lung Cancer; Malignant Mesothelioma; Metastatic Cancer
Interventions: Drug: alvocidib; Drug: romidepsin
Optical Coherence Tomography in the Detection of airway cells that are abnormal in Patients Undergoing Surgery for lung cancer or lung disease
Condition: Lung cancer; Malignant Mesothelioma, metastatic cancer; precancerous / Nonmalignant Condition
Interventions: Procedure: bronchoscopic and lung imaging studies; Procedure: diagnostic bronchoscopy; Procedure: histopathologic examination; Procedure: optical coherence tomography
Gene therapy for malignant pleural
Conditions: Pleural Mesothelioma; metastatic pleural effusion
Interventions: Gene Transfer: BG00001 (adenoviral-mediated interferon-beta)
A Study To Find The Best Dose Of SU011248 When Seeing With Pemetrexed, Pemetrexed And Cisplatin Or Pemetrexed and carboplatin in Patients With Advanced Solid Tumors
Condition: Mesothelioma; Non-Small Cell Lung Cancer; Neoplasm
Interventions: Drug: Sunitinib, Pemetrexed, Cisplatin, carboplatin
Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy (IPHC) to Treat Peritoneal Carcinomatosis
Condition: Stomach Neoplasms; colorectal neoplasm; Neoplasm Metastasis; Mesothelioma
Interventions: Procedure: cytoreductive surgery; Procedure: intraoperative peritoneal hyperthermic chemotherapy with cisplatin and mitomycin
Sublingual fentanyl spray in Treating Patients With Breakthrough Cancer Pain
Condition: Cancer
Interventions: Drug: fentanyl sublingual spray; Other: questionnaire administration
Study of Oral PXD101 in Patients With Advanced Solid Tumors or Lymphoma
Condition: Solid Tumors; Lymphoma
Interventions: Drug: belinostat
Electronic devices Record Cancer Symptoms in Patients With Advanced Cancer Receiving Palliative Care
Condition: Cancer
Interventions: Other: counseling intervention; Procedure: cognitive assessment; Procedure: fatigue assessment and management Procedure: psychosocial assessment and care; Procedure: quality of life assessment
Phase I Study of OSI-930 and Erlotinib in Cancer Tumor
Condition: Advanced Solid Tumor
Interventions: Drug: OSI-930 and erlotinib
1-methyl-d-Tryptophan in Treating Patients With Refractory Solid Tumor recurrence or
Condition: Cancer
Interventions: Drug: 1-methyl-d-tryptophan; Other: flow cytometry; Other: fluorescence activated cell sorting; Other high-performance liquid chromatography; Other: immunohistochemistry staining method; Other: laboratory marker analysis; Other: pharmacological study
An Analysis of Human Tumor Response microvascular endothelium to Ionizing Radiation
Condition: Ovarian neoplasms; colorectal neoplasm; Melanoma; Small Cell Lung Cancer; Liposarcoma
Intervention: Radiation: Ionizing radiation (IR) therapy; Radiation: Ionizing radiation (IR)
Study of Pemetrexed and bevacizumab in Patients With Head and Neck Cancer
Condition: Cancer
Interventions: Drug: Pemetrexed; Drug: bevacizumab
Study of Pemetrexed for Second-Line Pancreatic Cancer
Condition: Pancreatic Cancer
Interventions: Drug: pemetrexed
Continuous Hyperthermic peritoneal perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer
Condition: peritoneal neoplasms; retroperitoneal neoplasms; Gastrointestinal neoplasms; Adenocarcinoma; Neuroblastoma; ovarian neoplasms; Sarcoma; Adrenocortical Carcinoma; Wilms tumor; Rhabdomyosarcoma; Desmoplastic Small Round Cell Tumor
Interventions: Drug: CHPP of Cisplatin; Procedure: Abdominal Surge
Sunday, October 11, 2009
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